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Dear Mr. McCafferty,
Thank you for posting your request on History Hub!
We searched the National Archives Catalog and located the Central Decimal Files, 1910-1963 in the General Records of the Department of State (Record Group 59) that may contain the letter you see. There is a name index to this series. To request a search of the index, please contact the National Archives at College Park - Textual Reference (RDT2) via email at firstname.lastname@example.org. Please include as much information as possible in your email such as the full name of your ancestor and (if applicable) any variant spellings of her name.
We hope this information is helpful. Best of luck with your family research!