I have a great grandmother that we can find NO info on from her birth and life with her parents. she was born 1906, no info in 1910. 1920 living with uncle whom we knew raised her. in 1910 this same uncle had a sister living with him but she would have ha

What a challenge! It sounds like you've consulted census records, which can point to location of birth, residence information and other family members. You might also try seeking vital records such as birth or death. Also, turning to historical societies or local history collections where the person was born or lived, can be helpful. These institutions often have records like city directories which are not always available in a digitized format. Feel free to post her name and city/state of residence information to see if anyone in the History Hub community can provide more specific guidance!