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Hi Peggy. We have a small collection of Frances Cooke Macgregor's papers here at the FDR Presidential Library. I'd be happy to discuss the additional materials you have. If interested, please feel free to contact us at firstname.lastname@example.org.
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Besides the FDR library, you may wish to consult with the Hingham Public Library which has collection of Mrs. Macgregor's material. Frances Cooke Macgregor · Legendary Locals · Hingham Public Library Local History & Special Collections
Margaret Mead's papers are at the Library of Congress Margaret Mead papers and South Pacific Ethnographic Archives, 1838-1996 (Library of Congress Finding Aid) They may be interested in material relating to Mrs. Macgregor's time working with her.
The JFK Presidential Library JFK Library may be interested in any material relating to President Kennedy.